Publication

Patent & Publications:

Anu Naik, Jawad Alzeer, Therese Triemer, Annu Bujalska, Nathan W. Luedtke, Chemoselective modification of vinyl DNA by triazolinediones, Angewandte Chemie, Intl. Ed, 2017

Jawad Alzeer, Khaled Abou Hadeed: Ethanol and its Halal status in food industriesTrends in Food Science & Technology, 58, 2016, 14-20

figure.png

Jawad Alzeer: Swiss Scientific Society for Developing Countries: A Concept of Relationship, World Academy of Science, Engineering and Technology, International Science Index, Humanities and Social Sciences Vol:10, No:1, 2016, P. 374-377

1505397_1380600262204928_1006169148_n

Martin Seyfried, Jawad Alzeer, Nathan Luedtke: Molecular Design and Synthesis of Planar Telomestatin Analogue; European Journal of Organic Chemistry; 36, 2015, DOI: 10.1002/ejoc.201501103

picture

Zahra Aljabari, Jawad Alzeer, Rami Arafeh: Catechin detection in callus and in vitro cultures of the eastern strawberry tree, Arbutus Andrachne L., an endangered medicinal tree in Palestine, Global J Res. Med. Plants & Indigen. Med. | Volume 3, Issue 5 | May 2014 | 196–205

Arbutus_andrachne_fruits
Jawad Alzeer, Bala Vummidi, Rami Arafeh, Waleed Rimawi, Hatem Saleem, Nathan Luedtke: The influence of extraction solvents on the anticancer activities of Palestinian medicinal plants, J. Med. Plant Res. 2014, Vol. 8, P. 408-415

ABSTRACT_plants2
Bala Vummidi, F. Noreen, Jawad Alzeer, K. Moelling Nathan Luedtke: Photodynamic agents with anti-metastatic activities, ACS Chem. Biol., 2013, 8, 1737.

ABSTRACT_PDT
Bala Vummidi, Jawad Alzeer, Nathan Luedtke: Fluorescent probes for G-quadruplex structures, 2013, ChemBioChem. 2013, 14 (5): 540-58.

ABSTRACT_fluorescent_probes
Sarah. Hentschel, Jawad Alzeer, Todor. Angelov, Orlando. D. Schaerer, Nathan. W. Luedtke: Synthesis of DNA interstrand crosslinks using a photocaged nucleobase, Angew. Chemie Intl. Ed., 2012, 51, 3466. (English)

ICL
Sarah. Hentschel, Jawad Alzeer, Todor. Angelov, Orlando. D. Schaerer, Nathan. W. Luedtke: Synthese von DNA-Interstrang-Crosslinks unter Verwendung einer photoaktivierbaren Nucleobase. Angewandte Chemie, 2012, 124, 14, 3523–3526. (German)

mcontent-1

Jawad Alzeer, Nathan Luedtke: pH-Mediated Fluorescence and G-Quadruplex Binding of Amido Phthalocyanines, Biochemistry, 2010; 49 (20), pp 4339-4348.

ABSTRACT_amido_Pc
Manikandan Paramasivam, Alexandro Membrino, Susanna Cogoi, Jawad Alzeer, Nathan W. Luedtke, and Luigi E. Xodo: “Cellular uptake and G-4 DNA promoter binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes” Chem. Commun, 2010; 46 (4): 625.

image025

Jawad Alzeer, Bala Vummidi, , Phillipe J C Roth and Nathan Luedtke: “Guanidinium-Modified Phthalocyanines as High-Affinity G-Quadruplex Fluorescent Probes and Transcriptional Regulator” Angewandte Chemie, 2009; 48 (49): 9362. (English)

GPCs
Jawad Alzeer, Dr, Balayeshwanth R Vummidi, Phillipe J C Roth, Nathan W Luedtke, Guanidinium-modifizierte Phthalocyanine als Fluoreszenzso-nden mit hoherG-Quadruplex-Affinität und als Transkriptionsregulatoren Angewandte Chemie, 2009; 121: 49. 9526 (German)

mcontent

Jawad Alzeer, Philippe Roth, and Nathan Luedtke: “An efficient two-step synthesis of metal-free phthalocyanines using a Zn (II) templateChem. Commun, 2009; 15, 1970-1971.

abstract_metal_free_Pc
Nathan. W. Luedtke, Jawad Alzeer, Bala Vummidi, Preparation and uses of guanidinium-modified porphyrins and phthalocyanines, 2008, European Patent Patent No. 2010028780.

Jawad Alzeer, Orlando Schärer: “A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrands crosslinksNucleic Acid Research. 2006; 34 (16); 4458-4466

gkl587f1

Ludovic Gillet, Jawad Alzeer, Orlando Schärer: “Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified “ultra-mild” DNA synthesis crosslinksNucleic Acid Research. 2005; 33(6); 1961-1969.

image044

Jawad Alzeer, Jacques Chollet, Ingrid Heinze-Krauss, Christian Hubschwerlen, Hugues Matile, and Robert Ridley “Phenyl Methoxyacrylates: A New Antimalarial PharmacophoreJ. Med. Chem. 2000; 43 (4); 560-568.

jm990002yn00001

Jawad Alzeer, Jacques Chollet, Christian Hubschwerlen, Hugues Matile, and Robert Ridley “β-Alkoxyacrylates Against Malaria” European Patent Application No. 97111607.4, PCT/EP1998/004162, 1999 (WO/1999/002150).

Jawad Alzeer, Raffaello Masciadri, Nadine Nock, and Guy Wassner “MOM-protected 3-Hydroxy-5-phenyl-isoxazole: Regioselective Preparation and Synthetic ApplicationTetrahedron Lett., 1996, 37, 6857-6860.

1-s2.0-004040399601547X-gr1

Jawad Alzeer, and Andrea Vasella “Oligosaccharide Analogues of Polysaccharides Part 4. Synthesis of a Monosaccharide-Derived OctamerHelv. Chem. Acta., 1995, 78, 1219-1237.

Jawad Alzeer, and Andrea Vasella “Oligosaccharide Analogues of Polysaccharides Part 2. Regioselective Deprotection of Monosaccharide-Derived Monomers and DimersHelv. Chem. Acta., 1995, a78, 177-193.

Jawad Alzeer, Chengzhi Cai, and Andrea Vasella “Oligosaccharide Analogues of Polysaccharides Part 1. Concept and Synthesis of Monosaccharides-Derived MonomersHelv. Chem. Acta., 1995, 78, 242-264.

M. S. Shekhani, K. M. Khan, Jawad (Al) Zeer and W. Voelter “Useful Chiral Intermediates from Readily Available Carbohydrates200th National Meeting of the American Chemical Society, Washington, D. C., September 1990 ORGN 197.

Manuscripts, Poster & Book Citation

Jawad Alzeer, Balayeshwanth R. Vummidi, and Nathan W. Luedtke, “Cell-Permeable Fluorescent Probes with High Affinity for G-Quadruplex DNA and RNA” Second Second International Meeting on Quadruplex DNA April 18-21, 2009 Camberley-Brown Hotel, Louisville, KY, USA

Jawad Alzeer Balayeshwanth R. Vummidi, Phillipe J. C. Roth, and Nathan W. Luedtke, G-Quadruplex Fluorescent Probes as Transcriptional Regulator, 2nd Swiss-Japan Biomolecular Chemistry Symposium, 2009–SJBCS2009

Jawad Alzeer, Bala Vummid, Phillipe Roth, and Nathan Luedtke, “Structure-Selective Fluorescent Probes for G-Quadruplex DNA” Swiss chemical Society, fall meeting Zurich (Switzerland), 09.2008.

Jawad Alzeer, Orlando Schärer: “Synthesis and characterization of site-specific thymine-guanine DNA interstrand crosslinks” International roundtable on nucleosides, nucleotides and nucleic acids. 2006; XVII; PO030.

Jawad Alzeer, Jacques Chollet, Ingrid Heinze-Krauss, Christian Hubschwerlen, Hugues Matile, and Robert Ridley, Anne Schmitt Hoffmann: “β-methoxyacrylates, anovel class of antimalarial agents” Hoffmann La Roche, B-169’710; 1999.

Oligonucleotide synthesis using phosphoramidite chemistry, produced by Link Technologies Ltd., UK, Section 2.1, Ultramild Deprotection, Page 66

Theodora W. Greene, Peter G. Wuts “Protective groups in organic chemistry” third edition, John Wiley & Sons, Inc. NJ; 1999; Protection for the hydroxyl group-benzylether; P. 83, Protection for the alkyne-CH; P. 655.

F. Diederich, P. J. Stang, R. R. Tykwinski “Acetylene Chemistry: Chemistry, biology, and material science” 2005; Wiley-VCH Verlag GmbH & Co. KGaA. Acetylenosaccharides, Page 196.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s